Effect of CD4+ T-Cells and CD8+ T-Cells on Psoriasis: a mathematical study

Simple item page
dc.contributor.authorDatta, Abhirup
dc.contributor.authorKesh, Dipak Kumar
dc.contributor.authorRoy, Priti Kumar
dc.date.accessioned2021-05-17T09:58:57Z
dc.date.available2021-05-17T09:58:57Z
dc.date.issued2015
dc.descriptionPaper presented at the 3rd Strathmore International Mathematics Conference (SIMC 2015), 3 - 7 August 2015, Strathmore University, Nairobi, Kenya.en_US
dc.description.abstractPsoriasis is a common chronic inflammatory skin disease that is differentiated by repeated occurrences of raised scaly and red skin plaques. It is generated through several applications of drugs, strains, physical wounds to the skin and also for infectivity. Psoriasis is identified by composite interactions of T-Cells, Dendritic Cells, Cytokines and downstream transcription factors (type 1 Cytokines network). The effects of T-Cells in dermal layer (CD4+ T-Cells) are well-studied in the disease dynamics of Psoriasis from mathematical as well as biological context. But the concept of T-Cells in epidermal layer (CD8+ T-Cells) for disease progression of Psori-asis has not yet been explored till now from mathematical avenue. Here we introduce both CD4+ and CD8+ T-Cell, Dendritic Cell and Keratinocyte population to notice the impact of them on immunopathogenic cell-biological mechanism of Psoriasis. Numerical simulation is also furnished to establish the analytical outcomes.en_US
dc.identifier.urihttp://hdl.handle.net/11071/11901
dc.language.isoenen_US
dc.publisherStrathmore Universityen_US
dc.subjectT-Cellsen_US
dc.subjectDendritic cellsen_US
dc.subjectCD4+ T-Cellsen_US
dc.subjectCD8+ T-Cellsen_US
dc.subjectKeratinocytesen_US
dc.subjectDermal layeren_US
dc.subjectEpidermal layeren_US
dc.subjectCytokinesen_US
dc.titleEffect of CD4+ T-Cells and CD8+ T-Cells on Psoriasis: a mathematical studyen_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Effect of CD4+ T-Cells and CD8+ T-Cells on Psoriasis – a mathematical study.pdf
Size:
510.68 KB
Format:
Adobe Portable Document Format
Description:
Paper presented at the 3rd Strathmore International Mathematics Conference (SIMC 2015), 3 - 7 August 2015, Strathmore University, Nairobi, Kenya.
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
SIMC 2015