Show simple item record

dc.contributor.authorCole, Andrew Omandi
dc.date.accessioned2017-11-13T09:02:52Z
dc.date.available2017-11-13T09:02:52Z
dc.date.issued2017
dc.identifier.urihttp://hdl.handle.net/11071/5560
dc.descriptionA Dissertation submitted to the School of Graduate Studies in partial fulfillment for the Master of Science in Bio-Mathematics (MSc.BM) degree at Strathmore Universityen_US
dc.description.abstractAbout 240 people on earth contract HIV every hour according to the American Foundation for AIDS Research. Many researchers have put in millions of man hours in the quest to identify viable targets for identification and management of the viral infection. In this dissertation, an attempt is made to use available molecular data to identify unique genetics finger print profiles that can be used to reliably predict those at risk of HIV acquisition. Such unique genetic fingerprints could also be targets for future development of vaccines that may help in the quest for winning the fight against infection in the first place. Most laboratory kits for HIV will reliably identify those people already infected with the disease and a test that can identify those at risk or those that could benefit from future vaccination is timely. Such a discovery could go a long way in mitigating the tremendous effects of HIV infection on individuals and societies at large. My findings from the analysis show a good number of differentially expressed genes with the potential to build a reliable predictive model for HIV acquisition. More studies that are prospective in nature need to be conducted to further illuminate and characterize these potentially helpful findings.en_US
dc.language.isoenen_US
dc.publisherStrathmore Universityen_US
dc.subjectSusceptible- Infected modelen_US
dc.subjectGenetics finger printen_US
dc.subjectHIV acquisitionen_US
dc.subjectSusceptible Lymphocytesen_US
dc.titleTransmission of HIV partly depends on the relative population of, In-host, wild-type versus resistant susceptible lymphocytes: a study of sexually active femalesen_US
dc.typeThesisen_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record