A Bayesian hierarchical model for correlation in microarray studies
Abstract
Microarrays are miniaturised biological devices consisting of molecules (e.g. DNA or protein), called \probes", that are orderly arranged at a microscopic scale onto a solid support such as a nylon membrane or a glass slide.The array elements (probes) bind speci cally to labeled molecules, called "targets", into complex molecular mixtures,thereby generating signals that reveal the identity and the concentration of the interacting labeled cells.Microarray analysis has a broad range of applications that involve di erent types of probes and/or targets (cDNA or oligos)
Description
Paper presented at Strathmore International Math Research Conference on July 23 - 27, 2012
Microarrays are miniaturised biological devices consisting of molecules (e.g. DNA or protein), called \probes", that are orderly arranged at a microscopic scale onto a solid support such as a nylon membrane or a glass slide.The array elements (probes) bind specically to labeled molecules, called "targets", into complex molecular mixtures,thereby generating signals that reveal the identity and the concentration of the interacting labeled cells.Microarray analysis has a broad range of applications that involve dierent types of probes and/or targets (cDNA or oligos).
Microarrays are miniaturised biological devices consisting of molecules (e.g. DNA or protein), called \probes", that are orderly arranged at a microscopic scale onto a solid support such as a nylon membrane or a glass slide.The array elements (probes) bind specically to labeled molecules, called "targets", into complex molecular mixtures,thereby generating signals that reveal the identity and the concentration of the interacting labeled cells.Microarray analysis has a broad range of applications that involve dierent types of probes and/or targets (cDNA or oligos).