The HIV-HCV co-infection dynamics in absence of therapy

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dc.contributor.authorMayanja, Edison
dc.contributor.authorLuboobi, Livingstone S.
dc.contributor.authorKasozi, Juma
dc.contributor.authorNsubuga, Rebecca
dc.date.accessioned2021-05-10T14:46:12Z
dc.date.available2021-05-10T14:46:12Z
dc.date.issued2019-08
dc.descriptionPaper presented at the 5th Strathmore International Mathematics Conference (SIMC 2019), 12 - 16 August 2019, Strathmore University, Nairobi, Kenyaen_US
dc.description.abstractHIV-HCV co-infection is whereby an individual is infected with both viruses HIV and HCV. Globally, approximately 4 to 5 million people are co-infected with HIV and HCV. HCV infection significantly causes morbidity and mortality among HIV patients. HCV is known to progress faster and cause more liver-related health problems and death among people who are HIV/AIDS positive than those who are negative. Co-infection with HCV complicates the management of HIV/AIDS. Mathematical modeling generally provides an explicit framework by which we can develop and communicate an understanding of transmission dynamics of an infectious disease. In this article, a deterministic model is used in which ordinary differential equations are formulated and analyzed to study the HIV-HCV co-infection dynamics in absence of therapy. The findings reveal that the basic reproduction number for HIV-HCV co infection dynamics is equal to the maximum of single-disease basic reproduction numbers. This implies that the dynamics of the HIV-HCV co-infection will be dominated by the disease with the bigger basic reproduction numberen_US
dc.description.sponsorshipInstitute of Mathematical Sciences, Strathmore University, Nairobi, Kenya. Uganda Virus Research Institute London School of Hygiene and Tropical Medicine, Ugandaen_US
dc.identifier.urihttp://hdl.handle.net/11071/11802
dc.language.isoen_USen_US
dc.publisherStrathmore Universityen_US
dc.subjectHIV-HCVen_US
dc.subjectcc-infectionen_US
dc.subjectBasic reproduction numberen_US
dc.titleThe HIV-HCV co-infection dynamics in absence of therapyen_US
dc.typeArticleen_US
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