• Login
    View Item 
    •   SU+ Home
    • Research and Publications
    • Strathmore Institute of Mathematical Sciences (SIMs)
    • SIMs Publications
    • SIMs Scholarly Articles
    • View Item
    •   SU+ Home
    • Research and Publications
    • Strathmore Institute of Mathematical Sciences (SIMs)
    • SIMs Publications
    • SIMs Scholarly Articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Stochastic Model for Langerhans cells and HIV Dynamics in Vivo

    Thumbnail
    View/Open
    Working paper (482.9Kb)
    Author
    Mbogo, Rachel Waema
    Luboobi, Livingstone S.
    Odhiambo, John W.
    Metadata
    Show full item record
    Abstract
    Many aspects of the complex interaction between HIV and the human immune system remain elusive. Our objective is to study these inter-actions, focusing on the speci c roles of langerhans cells (LCs) in HIV infection. In patients infected with HIV, a large amount of virus is as-sociated with LCs in lymphoid tissue. To assess the influence of LCs on HIV viral dynamics during anti-retroviral therapy, we present and analyse a stochastic model describing the dynamics of HIV, CD4+ T-cells, and LCs interactions under therapeutic intervention in vivo. We per-form sensitivity analyses on the model to determine which parameters and/or which interaction mechanisms strongly affect infection dynamics.
    URI
    http://hdl.handle.net/11071/3681
    Collections
    • SIMs Scholarly Articles [20]

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV
     

     

    Browse

    All of SU+Communities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    Login

    DSpace software copyright © 2002-2016  DuraSpace
    Contact Us | Send Feedback
    Theme by 
    Atmire NV