Browsing by Subject "Colorectal cancer"

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    • Adaptation of a RAS pathway activation signature from FF to FFPE tissues in colorectal cancer 

      Omolo, Bernard; Yang, Mingli; Lo, Fang Yin; Schell, Michael J.; Austin, Sharon; Howard, Kellie; Madan, Anup; Yeatman, Timothy J. (Strathmore University, 2017)
      Background: The KRAS gene is mutated in about 40 % of colorectal cancer (CRC) cases, which has been clinically validated as a predictive mutational marker of intrinsic resistance to anti-EGFR inhibitor (EGFRi) therapy. ...