Browsing SIMC 2017 by Title
Now showing items 1-20 of 85
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Adaptation of a RAS pathway activation signature from FF to FFPE tissues in colorectal cancer
(Strathmore University, 2017)Background: The KRAS gene is mutated in about 40 % of colorectal cancer (CRC) cases, which has been clinically validated as a predictive mutational marker of intrinsic resistance to anti-EGFR inhibitor (EGFRi) therapy. ... -
Analysis of a mathematical model of influenza dynamics with drug resistance aspect
(Strathmore University, 2017)Influenza has posed a terrific public health concern. It has led to unacceptably high mortality rates especially to immune compromised persons worldwide. Efforts to effectively treat and combat the spread of influenza can ... -
Analysis of categorical data in presence of latent random effects using Structural Equation Modeling: an application
(Strathmore University, 2017)In most medical research, of interest is to establish the causal relationships that exist between variables which may be direct or indirect. This research intends to use structural equation modeling technique to analyze ... -
Banana Xanthomonas Wilt dynamics with mixed cultivars in a periodic environment
(Strathmore University, 2017)In this study, a non-autonomous model for the spread of Banana Xanthomonas Wilt disease (BXW) in a seasonally fluctuating environment is considered. Two categories of cultivars with different susceptible levels for ... -
Bayesian analysis of Multivariate Stochastic Volatility models
(Strathmore University, 2017)Multivariate stochastic volatility (MSV) models have gained applicability in Time Series (TS) data for analyzing multivariate financial and economic time series because they capture the volatility dynamics. Bayesian prior ... -
Bayesian estimation of Multivariate Stochastic Volatility by applying state space models
(Strathmore University, 2017)This work seeks to apply a Bayesian analysis in estimating multivariate stochastic volatility (MSV) using state space models. A multiplicative model based on inverted Wishart and multivariate singular beta distributions ... -
Bernoulli collocation method for solving linear multi-dimensional diusion and wave equations with Dirichlet boundary conditions
(Strathmore University, 2017)In this paper, a numerical approach is proposed for solving multi-dimensional parabolic diusion and hyperbolic wave equations subject to the appropriate initial and boundary conditions. The considered numerical solutions ... -
Blood perfusion flow of an electro-kinetic fluid through a porous medium with viscous dissipation
(Strathmore University, 2017)In this work, we considered a mathematical model of an electro-kinetic fluid flow through a porous medium with blood perfusion and viscous dissipation. The fluid is assumed to poses temperature-dependent variable viscosity ... -
Cancer cases in Kenya; forecasting incidents using box & amp; Jenkins Arima Model
(Strathmore University, 2017)The aim of the study was to fit appropriate time series models in assessing the accuracy of the Box Jenkins and ARIMA model in forecasting of Cancer case admissions for all people of any age from different health facilities ... -
Certain properties of the essential spectra in Banach spaces
(Strathmore University, 2017)Let X be an arbitrary Banach space, and L (X) be the set of all bounded linear operators on X. We apply closed range theorem to determine some duality properties of the essential spectrum on L(X). Specifically, we introduce ... -
Comparison of binary diagnostic predictors using entropy
(Strathmore University, 2017)The use of gold standard procedures in screening may be costly, risky or even unethical. It is usually therefore, not admissible for large scale application. In this case, a more acceptable diagnostic predictor is applied ... -
A Comparison of the Bayesian regression and the Ordinary Least Squares regression
(Strathmore University, 2017)The ordinary least squares regression model assumes that there are enough data to make inference about the parameters. For Bayesian regression however, the data are supplemented with additional information in the form of ... -
A Computational investigation on the dynamics of shallow water waves
(Strathmore University, 2017)The dynamics of shallow water waves has been an active research area for the past several decades. In this context, there are several models that govern this wave flow. In this study, finite element method based on B-spline ... -
Correlation between Malaria and Pneumonia in Kwale County, Kenya
(Strathmore University, 2017)Malaria and Pneumonia have been the major causes of morbidities and mortilities in Kwale county in the past years. Majority of the people in the county who get pneumonia have a higher incidence of Malaria. Thus, even though ... -
Drought prediction numerical model in North - Eastern region of Kenya
(Strathmore University, 2017)Numerical models are essential tools applied in predicting drought on day to day basis that involves taking current observations of weather and processing the data with the models to forecast the future state of weather ... -
Dynamic TCP pacing for Delay Intolerant Cloud Communications
(Strathmore University, 2017)In the recent years, many organizations have turned to cloud technology to support their information technology services. The cloud servers are therefore increasingly holding huge and sensitive information belonging to ... -
Effect of collaborative peer learning on learner attitude and performance in Mathematics in Kenya
(Strathmore University, 2017)Learners learn best when they are actively engaged in the processing of learning information. One method of involving them in active learning is to have them learn from each other in small groups or teams. Research shows ... -
Empirical density estimation and back-testing of Value at Risk (VaR) from parametric volatility models
(Strathmore University, 2017)This paper forecasts one-day-ahead foreign exchange volatility using parametric models and compares their empirical forecasting performance of Value at Risk of five spot exchange rates; namely, the Kenyan Shilling versus ... -
An Empirical performances comparison of meta-heuristic algorithms for school bus routing problem
(Strathmore University, 2017)School Bus Routing Problem is an NP-hard Combinatorial Optimization problem, and hence solving the School Bus Routing Problem, requires the application of one or more of the metaheuristic algorithms. This work presents a ... -
Estimating covariance matrix with high frequency data for Currency Portfolio Optimization
(Strathmore University, 2017)The covariation between asset returns plays a crucial role in modern finance both in portfolio optimization and risk management. The paper is an effort towards estimating a covariance matrix using high-dimensional, ...